Comparative study between complete blood picture indices and presepsin as early prognostic markers in septic shock patients

Background: Outcome prediction in septic shock is a prime concern as it may facilitate more aggressive interventions to be made at appropriate time to reduce costs and mortality. We evaluated combining complete blood count (CBC) indices [red cell distribution width (RDW), mean platelet volume (MPV), neutrophil–lymphocyte ratio (NLR)] for septic shock early prognosticationin comparison to presepsin.

Methods: Sixty adult intensive care unit (ICU) patients with septic shock according to Sepsis-3 were enrolled. Blood assembling on admission and day 3 to determine presepsin level, and CBC indices which were interpreted as RDW, MPV, and NLR. Patients were sorted into survivors (Group I) and non-survivors (Group II).