Diagnostic and prognostic value of serum presepsin in cirrhotic patients with spontaneous bacterial peritonitis

Hepatitis C virus (HCV) is a major health problem affecting 170 million people worldwide. The WorldHealth Organization (WHO) estimated in 2011 that Egypt comes first worldwide in HCV prevalence,with chronic infection leading to fibrosis of the liver and ultimately to cirrhosis. SBP (Spontaneous Bacterial Peritonitis) is one of the most frequent and life-threatening complications of patients with cirrhosis. It is an infection of ascitic fluid that cannot be attributed to any intra-abdominal, ongoing inflammatory, or surgically correctable condition. More than 92% of all cases of SBP are monomicrobial. Gram-negative bacteria remain the most common pathogens in SBP.