Diagnostic Value of Presepsin in Sepsis

Introduction: Sepsis, severe sepsis and septic shock are some of the most common conditions managed in the emergency room and Intensive Care Units (ICU), with the mortality remaining between 30 and 60 despite antibiotic therapy and cardiovascular and respiratory support. Sepsis is defined as the presence (likely or documented) of infection along with systemic manifestations of infection. Severe sepsis is defined as sepsis plus organ dysfunction or tissue hypoper fusion induced by sepsis. Septic shock is hypoper fusion induced by persistent sepsis despite adequate fluid resuscitation [1,2].