Low Levels of Procalcitonin or Presepsin Combined with Significantly Elevated C-reactive Protein May Suggest an Invasive Fungal Infection in Hematological Patients With Febrile Neutropenia

Infectious complications in immunocompromised patients with neutropenia or on long-lasting immunosuppressive treatments are a serious issue. Invasive fungal infections (IFIs) represent cases in which delayed or inappropriately targeted treatments can have fatal consequences. Today, Aspergillus spp. and Candida spp. are the 2 most important genera accounting for about 95% of all cases of IFIs.