The False Positive Soluble CD 14 Subtype is Lower Than That of Procalcitonin in Postoperative Severe Elective Surgery Patients: A Prospective Observational Trial
Background
The soluble CD14 subtype, presepsin (P-SEP), has been reported to be a novel diagnostic marker for sepsis. Clinicians must have knowledge about false positive biomarkers. There have been reports about elevation of the P-SEP level in patients with renal dysfunction, but reports about surgical insult have been few. In this study, we focused on surgical insult and evaluated the hypothesis that the false positive rate after surgical insult is lower for P-SEP than for procalcitonin (PCT).