PRESEPSIN AND PROCALCITONIN – MARKERS OF SEPSIS AND SEVERE PNEUMONIA
Markers of inflammation procalcitonin (PCT), presepsin (PSP) are used against pneumonia, sepsis. The research objective was to study PCT, PSP to improve the diagnosis of severe pneumonia, sepsis. There was totally evaluated 172 patients at the age from 17 to 87. Out of them 118 patients had community-acquired pneumonia (CAP), sepsis, other purulent diseases. These patients were investigated for the level of PCT. PCT was determined quantitatively in ng/ml by the immunofluorescence analyzer miniVIDAS (Biomerye, France). 54 patients with pneumonia, sepsis and other inflammatory diseases have been investigated for the level of the presepsin. Presepsin level was determined quantitatively in pg/ml by means of chemiluminescent immunoassay analyzer Pathfast (Mitsubishi Chemical Medience Corporation, Japan). All patients had received antibacterial therapy in other health care organizations before entering the hospital.